Presence of the adenovirus E1A-like activity in preimplantation stage mouse embryos.
Open Access
- 1 August 1988
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 8 (8) , 3553-3555
- https://doi.org/10.1128/mcb.8.8.3553
Abstract
The presence of the adenovirus E1A-like activity in embryonal carcinoma stem cells has been reported. We now show that preimplantation stage mouse embryonic cells allow transcription of the E1A-dependent E2A gene when infected with E1A-deleted mutant dl312, indicating the presence of the E1A-like activity in morulae and blastocysts. Moreover, such activity seems to decrease or disappear at about the time of implantation.This publication has 21 references indexed in Scilit:
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