Phosphoglucomutase Mutants of Neurospora sitophila and Their Relation to Morphology
- 1 July 1970
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 66 (3) , 638-645
- https://doi.org/10.1073/pnas.66.3.638
Abstract
Biochemical and genetic evidence is presented that the rg-1 and rg-2 genes control the structure of the two isozymes of phosphoglucomutase (Phosphoglucomutase I and II) in Neurospora silophila. Results of kinetic and gel filtration studies show that the two phosphoglucomutases may exist in vitro either as separate or as a single but complex molecular species depending on the ionic concentration. The complex phosphoglucomutase molecule is suggested to be the physiologically active form of the enzyme. The change in the enzyme structure is discussed in relation to the morphological change in the ragged mutant strains.Keywords
This publication has 13 references indexed in Scilit:
- A Molecular Basis for HeterosisScience, 1969
- Isoenzymes of phosphoglucomutaseBiochemistry, 1969
- Phosphoglucomutase. V. Multiple forms of phosphoglucomutase.Proceedings of the National Academy of Sciences, 1967
- The Phosphoglucomutase, Phosphoglyceric Acid Mutase, and Phosphomannose Isomerase Activities of Arterial Tissue in Individuals of Various AgesJournal of Gerontology, 1966
- Stimulation of fatty acid biosynthesis by phosphorylated sugars.Proceedings of the National Academy of Sciences, 1966
- Subunit association and catalytic activity of uridine diphosphate galactose-4-epimerase from yeast.Proceedings of the National Academy of Sciences, 1966
- The effect of mutation on two forms of phosphoglucomutase in SaccharomycesBiochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 1964
- Estimation of the molecular weights of proteins by Sephadex gel-filtrationBiochemical Journal, 1964
- Spermidine in the Bacterial CellJournal of General Microbiology, 1961
- Metabolic blocks in carbohydrate metabolism in diabetes.1951