Interpretative criteria for the agar diffusion susceptibility test with azithromycin
- 1 November 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 22 (5) , 637-641
- https://doi.org/10.1093/jac/22.5.637
Abstract
Azithromycin (CP-62,993) is a macrolide with a tendency to concentrate in various body tissues. Difficulties that arise when establishing tentative minimum inhibitory concentration (MIC) breakpoints for such a drug include the question of whether MICs should be compared with the achievable concentrations in blood or in tissue. Pending clinical experience with this drug, we recommend the following tentative criteria for interpreting tests with 15 μg azithromycin discs: susceptible ≥18 mm (MIC ≤2mg/l) and resistant ≤13mm (MIC ≥ mg/l).Keywords
This publication has 3 references indexed in Scilit:
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- Spectrum and mode of action of azithromycin (CP-62,993), a new 15-membered-ring macrolide with improved potency against gram-negative organismsAntimicrobial Agents and Chemotherapy, 1987