Quantity of anti-leucoprotease relative to α1-proteinase inhibitor in peripheral airspaces of the human lung
- 1 October 1988
- journal article
- research article
- Published by Portland Press Ltd. in Clinical Science
- Vol. 75 (4) , 351-353
- https://doi.org/10.1042/cs0750351
Abstract
Peripheral airspaces were selectively lavaged using balloon-tipped catheters of 2 mm diameter. Molar anti-leucoprotease/.alpha.1-proteinase inhibitor ratios as determined in these lkavage fluids by enzyme immunoassays ranged from 0.02 to 0.14 (mean 0.08). These data indicate that peripheral airspaces contain minor amounts of anti-leucoprotease relative to .alpha.1-proteinase inhibitor. This observation does not necessarily mean that anti-leucoprotease is of minor importance in protecting the lung interstitium.This publication has 2 references indexed in Scilit:
- Concentration of bronchoalveolar lavage fluid by ultrafiltration: Evidence of differential protein loss and functional inactivation of proteinase inhibitorsAnalytical Biochemistry, 1985
- Quantitation of Human Granulocyte Protease Inhibitors in Non-Purulent Bronchial Lavage FluidsActa Oto-Laryngologica, 1978