Harvesting the mouse genome
Open Access
- 19 August 2002
- journal article
- Published by Wiley in Comparative and Functional Genomics
- Vol. 3 (4) , 319-324
- https://doi.org/10.1002/cfg.198
Abstract
The sequencing of the black 6 mouse (strain C57Bl/6) has reached an important juncture. The BAC fingerprint map is almost complete, the BACs have been endsequenced and a seven-fold coverage whole-genome shotgun has been assembled. Now the BAC-by-BAC sequencing phase is under way and in-depth comparative analysis can be carried out on regions that have been the subject of targeted sequencing. This paper reviews the progress so far and looks forward to the promises of finished sequence.Keywords
This publication has 7 references indexed in Scilit:
- High-Throughput Gene Mapping in Caenorhabditis elegansGenome Research, 2002
- Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significanceMammalian Genome, 2002
- New 3′ elements control Pax6 expression in the developing pretectum, neural retina and olfactory regionMechanisms of Development, 2002
- ARACHNE: a whole-genome shotgun assembler.2002
- PipMaker—A Web Server for Aligning Two Genomic DNA SequencesGenome Research, 2000
- Complete sequencing of the Fugu WAGR region from WT1 to PAX6: Dramatic compaction and conservation of synteny with human chromosome 11p13Proceedings of the National Academy of Sciences, 1998