INHALATION THERAPY OF BRONCHIAL ASTHMA
- 1 April 1939
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 112 (13) , 1223-1226
- https://doi.org/10.1001/jama.1939.02800130007003
Abstract
The possibility of obtaining relief of asthmatic symptoms by the direct application of a solution of epinephrine to the bronchial mucosa was reported by Ephraim1as early as 1910. Through the bronchoscope he first observed blanching of the mucous membrane after subcutaneous administration of epinephrine. Subsequently, epinephrine solution was sprayed directly into the bronchi through the bronchoscope with definite relief of asthmatic symptoms. In a later communication Ephraim2repeated these observations and commented on the beneficial effect of procaine hydrochloride alone, although he said that greater benefit resulted from the epinephrine. Thereafter, other authors reported the efficacy of the inhalation of epinephrine solutions for the relief of asthmatic symptoms. The earler of these were Krause,3Segel4and Zuelzer.5In later years a number of reports have been made concerning this procedure, such as those of Grunwald,6Sachse,7Weiss and Magassy,8Camps,9Keywords
This publication has 0 references indexed in Scilit: