DEPRESSION OF ANAEROBIC GLYCOLYSIS OF EMBRYONIC TISSUE BY WESTERN STRAIN OF EQUINE ENCEPHALOMYELITIS VIRUS. PREVENTION OF THIS EFFECT BY SPECIFIC IMMUNE SERUM

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Abstract
Whole chick embryo, chick embryo from which brain and spinal cord had been removed, and embryonic skeletal muscle were employed. Equine encephalomyelitis virus (Western strain) (W.E.E.) depressed the rate of anaerobic glycolysis of the embryonic tissues within 2 days after its addition to the tissue; the depression varied from 17-82% and was apparent 2-4 days after addition of the virus. No significant effect of the virus was observed 4 hrs. and 6 days after mixing it with the tissue. Anti-W.E.E. immune serum prevented the inhibiting action of W.E.E. virus on the anaerobic glycolysis of embryonic skeletal muscle.

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