Oseltamivir and Risk of Lower Respiratory Tract Complications in Patients With Flu Symptoms: A Meta-analysis of Eleven Randomized Clinical Trials
Open Access
- 15 June 2011
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 53 (3) , 277-279
- https://doi.org/10.1093/cid/cir400
Abstract
An independent reanalysis of 11 randomized clinical trials shows that oseltamivir treatment reduces the risk of lower respiratory tract complications requiring antibiotic treatment by 28% overall (95% confidence interval [CI], 11%–42%) and by 37% among patients with confirmed influenza infections (95% CI, 18%–52%).Keywords
This publication has 14 references indexed in Scilit:
- Review: Neuraminidase inhibitors relieve influenza symptoms and reduce laboratory-confirmed influenza in healthy adultsAnnals of Internal Medicine, 2010
- Roche replies to the authors of the Cochrane Review on oseltamivirBMJ, 2009
- Why don't we have all the evidence on oseltamivir?BMJ, 2009
- Neuraminidase inhibitors for preventing and treating influenza in healthy adults: systematic review and meta-analysisBMJ, 2009
- Influenza Will Not Miss OpportunitiesClinical Infectious Diseases, 2006
- Impact of Oseltamivir Treatment on Influenza-Related Lower Respiratory Tract Complications and HospitalizationsArchives of internal medicine (1960), 2003
- Safety and Pharmacology of Oseltamivir in Clinical UseDrug Safety, 2003
- Efficacy and safety of oseltamivir in treatment of acute influenza: a randomised controlled trialThe Lancet, 2000
- Efficacy and Safety of the Oral Neuraminidase Inhibitor Oseltamivir in Treating Acute InfluenzaJAMA, 2000
- Clinical Efficacy and Safety of the Selective Oral Neuraminidase Inhibitor Oseltamivir in Treating Acute InfluenzaKansenshogaku Zasshi, 2000