Prevalence of HIV infection in pregnant women in London and elsewhere in England

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Abstract
Specimens were grouped by antenatal centre, calendar quarter in which serum was collected, and age (four age groups) and were irreversibly unlinked from the source women. Specimens were tested with a commercial HIV-1 and HIV-2 enzyme immunoassay (Wellcozyme HIV1+2); repeatedly reactive specimens were tested by other assays, including western blotting, at the national reference laboratory.1 We used logistic regression analyses to model the variation in the number of tests that yielded positive results for HIV infection, allowing for differences among study centres and the relation between the prevalence of HIV-1 infection and time, age group, and centre.