Palladium(0)-mediated intramolecular lactonization of allylic alcohol derivatives; unusual substituent effect of the trifluoromethyl group on δ-lactone formation

Abstract
In the Intramolecular lactonization of allylic alcohol derivatives catalysed by a palladium(0) complex, selective formation of 4,6-cis-disubstituted δ-lactones and the unusual effect of a trifluoromethyl group in the homoallylic position were observed.