Effect of Dialysate Temperature and Flow Rate on Peritoneal Clearance

Abstract
Intermittent peritoneal dialysis was performed to observe the effect of dialysate temperature and flow rate on peritoneal clearance. At the same hourly flow rates, the dialysate heated to 37 C had a 35% greater clearance than the dialysate at 20 C. The most efficient method of dialysis with commercially available equipment is a repeated 2-liter exchange of dialysate at 37 C with no pause between inflow and outflow. This method in an average dialysate volume of 3.3 liters/hr and an average urea nitrogen clearance of 20.8 ml/min.

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