Current Progress on Esterases: From Molecular Structure to Function
- 1 May 2002
- journal article
- Published by Elsevier in Drug Metabolism and Disposition
- Vol. 30 (5) , 488-493
- https://doi.org/10.1124/dmd.30.5.488
Abstract
This article reports on a symposium sponsored by the American Society for Pharmacology and Experimental Therapeutics and held at the April 2001 Experimental Biology meeting. Current developments in molecular-based studies into the structure and function of cholinesterases, carboxylesterases, and paraoxonases are described. This article covers mechanisms of regulation of gene expression of the various esterases by developmental factors and xenobiotics, as well as the interplay between physiological and chemical regulation of enzyme activity.Keywords
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