Cerebrospinal fluid and serum levels of magnesium, zinc, and calcium in man

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Abstract
Analysis of Mg, Zn, and Ca concentrations in serum and cerebrospinal fluid indicates a different ratio for each and suggests a different mechanism for production of the distinctive cerebrospinal fluid content. Cerebrospinal fluid was found to bear a linear relationship to serum Mg in conditions with chronic depression of serum Mg A loss or reversal of the normal ratio occurred in 2 patients with ischemic cerebrovascular disease and in 2 patients with inflammatory central nervous system disease.