Development of Pathogenicity‐Driven Definitions of Outcomes for a Field Trial of a Killed Oral Vaccine against EnterotoxigenicEscherichia coliin Egypt: Application of an Evidence‐Based Method
Open Access
- 15 June 2004
- journal article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 189 (12) , 2299-2307
- https://doi.org/10.1086/386288
Abstract
Background. To design an efficacy trial of a killed oral vaccine against enterotoxigenic Escherichia coli (ETEC) diarrhea in Egyptian children, we derived for ETEC diarrhea an empirical definition that increased the probability that diarrhea associated with excretion of ETEC was caused by the detected ETEC.Keywords
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