A Comparative Study of Five Immunologic Pregnancy Tests: An Analysis of 1,863 Cases

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Abstract
A prospective study of five commercially available pregnancy tests was performed on 1,863 urine specimens, including 724 specifically selected because of interfering substances in the specimen or because of a clinical state capable of causing such substances to be excreted. The accuracies of the various tests, based on the total numbers of correct test results from uncomplicated first trimester pregnancies and a control group of nonpregnant patients, were 98.8% for the Pregnosticon tube test, 98.6% for the UCG tube test, 96.7% for the Pregnosticon slide test, 93.8% for the Gravindex test, and 93.2% for the DAP test. Because of their greater sensitivity and accuracy, the tube tests should be used for all patients having elective gynecologic surgery. Of the three 2-min. slide tests, the least number of false positive test results were recorded with the Pregnosticon slide test. With the latex agglutination-inhibition slide tests, most false positive or inconclusive test results were related to protein or blood in the test specimen.

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