CORNEAL VASCULARIZATION IN RATS ON A TRYPTOPHANE DEFICIENT DIET

15 June 1945

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 101 (2633) , 619
https://doi.org/10.1126/science.101.2633.619

Abstract

9 rats were given daily a freshly prepared soln. containing 30 [gamma]/ml. of riboflavin and 9 control rats received tap water instead. Both groups were fed on a tryptophane deficient diet. In both groups corneal vascularization and cataracts developed with equal rapidity and incidence. After 5 wks. riboflavin was discontinued and both groups received tryptophane. They gained wt. and recovered completely from corneal lesions with partial recovery from cataracts.