AN INFLUENZA VIRUS PNEUMONIA OF MICE THAT IS NONTRANSFERABLE BY SERIAL PASSAGE

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Abstract
Mice inoculated intranasally with allantoic fluids infected with the egg-adapted Cam strain of influenza A prime virus died on the 3d or 4th day with complete pulmonary consolidation, but suspensions of lungs obtained from those animals did not produce pulmonary lesions when introduced into the lungs of normal mice. The data indicate that the virus particles were the lethal agents, but that only a small percentage of those particles multiplied in the lung tissue.

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