Lipoprotein Retention—and Clues for Atheroma Regression
- 1 August 2005
- journal article
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 25 (8) , 1536-1540
- https://doi.org/10.1161/01.ATV.0000174795.62387.d3
Abstract
Subendothelial retention of apoB-lipoproteins is the key initiating event in atherosclerosis, provoking a cascade of pathogenic responses. Dissection of the molecular participants provides fresh insight into how this major killer might be reversed. Efflux of harmful lipids derived from retained lipoproteins may be crucial in promoting beneficial remodeling of lesions.Keywords
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