Cardioplegic arrest does not increase the risk of atrial fibrillation after coronary artery bypass surgery

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Abstract
Objective: Atrial fibrillation (AF) is the most common arrhythmia after coronary artery bypass grafting (CABG). It is a considerable source of morbidity, prolongs hospital stay and increases costs of treatment. Atrial cannulation, cardiopulmonary bypass and cardioplegic arrest have been suggested to play a role in the development of AF after CABG. The aim of this case-control study was to evaluate the role of cardiopulmonary bypass and cardioplegic arrest in the development of postoperative AF. Methods: Data from 114 patients undergoing CABG without cardiopulmonary bypass and cardioplegic arrest (off-pump) between October, 1998 and December, 2002 were evaluated for the occurrence of postoperative AF. Each patient was individually matched by gender, age (±3 years), left ventricle ejection fraction (±5%), history of myocardial infarction, unstable angina, and β-blocker medication with patients undergoing CABG with cardiopulmonary bypass and cardioplegic arrest (on-pump) during the same period. The data from off-pump and on-pump groups were compared. Results: Off-pump and on-pump groups had similar preoperative characteristics. The number of distal anastomoses was lower in the off-pump (2.3±0.9) than in the on-pump (3.9±1.1, PConclusions: Neither cardiopulmonary bypass nor cardioplegic arrest increases the risk of postoperative AF after CABG.

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