Effect of early thymectomy on the cellular changes occuring in the spleen of the clawed toad following administration of soluble antigen.

  • 1 April 1974
    • journal article
    • Vol. 26  (4) , 797-807
Abstract
Xenopus toadlets thymectomized as larvae at 8 days post-fertilization developed relatively normal lymphoid tissues but the spleen was reduced in weight. The increase in numbers of pyroninophilic cells and in the size of the white pulp regions which occurs in the spleen of intact, control Xenopus in response to administration of human γ-globulin (HGG) in adjuvant was less marked in thymectomized animals.