Potent and Selective Peptide Agonists of α-Melanotropin Action at Human Melanocortin Receptor 4: Their Synthesis and Biological Evaluation in Vitro
- 24 August 2001
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 286 (3) , 641-645
- https://doi.org/10.1006/bbrc.2001.5444
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Melanocortin receptors: new opportunities in drug discoveryExpert Opinion on Therapeutic Patents, 2001
- Analogs of Lactam Derivatives of α-Melanotropin with Basic and Acidic ResiduesBiochemical and Biophysical Research Communications, 2000
- Analogs of MTII, Lactam Derivatives of α-Melanotropin, Modified at the N-Terminus, and Their Selectivity at Human Melanocortin Receptors 3, 4, and 5Biochemical and Biophysical Research Communications, 1999
- Structure-function studies on the cyclic peptide MT-II, lactam derivative of α-melanotropinPeptides, 1999
- Melanocortin mediated inhibition of feeding behavior in ratsNeuropeptides, 1998
- Cyclic lactam .alpha.-melanotropin analogs of Ac-Nle4-cyclo[Asp5,D-Phe7,Lys10]-.alpha.-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptorsJournal of Medicinal Chemistry, 1995
- .alpha.-Melanotropin: the minimal active sequence in the frog skin bioassayJournal of Medicinal Chemistry, 1987
- ACTH-(1–24) and α-MSH antagonize feeding behavior stimulated by kappa opiate agonistsPeptides, 1986
- The bio‐organic chemistry of α‐melanotropinMedicinal Research Reviews, 1982
- 4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity.Proceedings of the National Academy of Sciences, 1980