Collagen-Coated Cellulose Sponge: Three-Dimensional Matrix for Tissue Culture of Walker Tumor 256
- 10 March 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 155 (3767) , 1259-1261
- https://doi.org/10.1126/science.155.3767.1259.b
Abstract
Three-dimensional growth of large populations of cells in vitro has been observed in the interstices of a matrix consisting of collagen-coated cellulose sponge. The growth of Walker tumor 256 in this composite matrix is compared with that found in a matrix composed of either cellulose sponge alone or collagen sponge alone. The composite matrix is superior to either one. Collagen-coated cellulose sponge may provide a simple tool for the study of social interaction of cells in the formation of organized elementary tissue structures.Keywords
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