Editorial Commentary: The Sound of Hoof Beats Does Not Always Mean That It Is a Zebra

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Abstract
The article by Causer et al. [1] is very timely in this age of increasing international travel, drug-resistant malaria, and concerns about the safety of antimalarial drugs. The phenomenon of “chemoprophylaxis failure” described by Causer et al. [1] is by no means new, because it has been known to exist anecdotally by tropical disease practitioners for many years, but it is likely to be unrecognized by a majority of infectious diseases consultants. This article highlights the problem of misdiagnosis of malaria among travelers to developing countries and raises a number of very important issues.