UPPER GASTRO-INTESTINAL DISEASE ASSOCIATED WITH SYPHILIS

21 January 1928

journal article
research article
Published by American Medical Association (AMA)

Vol. 90 (3) , 175-180
https://doi.org/10.1001/jama.1928.02690300015005

Abstract

During the past three years we have studied twenty-three patients with pathologic manifestations at the upper end of the digestive tube in which the possibility of gastro-intestinal syphilis had to be considered. It is the opinion of most students of syphilis that the disease rarely involves the gastro-intestinal tract. Stokes and Brown¹found gastric syphilis in only 4 per cent of 200 syphilitic patients whose chief complaint was stomach trouble. Symmers,²in reviewing 4,880 necropsies at Bellevue, reported only one case of gastric syphilis (Pappenheimer's case). Chiari³reports finding two cases of gastric syphilis in a series of 243 autopsies on syphilitic patients. McNeil,⁴in a series of 1,200 persons with syphilis, found ninety-seven complaining of gastric symptoms, which arose from gastric syphilis in only three. Hartwell⁵states that approximately 200 cases are reported in the literature. He is of the opinion that a great

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