THE RATE OF GROWTH AND NATURAL DURATION OF PRIMARY BRONCHIAL CANCER

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Abstract
An additional series of 19 patients confirms the growth rate findings reported in an earlier series of 40 patients with primary untreated bronchial cancer. The duration of growth of this type of cancer is much longer than has previously been believed. For example, an "average" peripheral squamous cell cancer requires approximately 8 years to reach a diameter of about 2 cm., and a peripheral adenocarcinoma requires about 16 years to reach that size. It is probable that during this long phase (most of it pre-clinical, and not recordable on standard roentgenograms), metastasis occurs, rendering this tumor so difficult to eradicate.

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