Abstract
Background: Patients with peripheral arterial occlusive disease (PAD) experience deteriorating ambulatory function and consequently impaired quality of life (QOL). QOL in patients receiving prostaglandin E1 in lipid microspheres (lipo-PGE1; Liple®) for the treatment of PAD has not been evaluated using the Japanese version of the Walking Impairment Questionnaire (WIQ). Methods and Results: Data from 169 patients (98 men, 71 women; mean [median] age, 74±10 [74] years) with an ankle-brachial pressure index 1 treatment (PConclusions: WIQ is a valid tool for evaluating therapeutic response in patients with PAD. Lipo-PGE1 improves QOL as evaluated by patients themselves. (Circ J 2010; 74: 365-370)

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