ADRENAL CORTICAL FUNCTION IN PATIENTS WITH TETANUS

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Abstract
Plasma cortisol concentrations have been measured in fifteen patients with tetanus at 2–3–day intervals throughout the period of treatment. The concentration at 9 a.m. was usually within the normal range, whereas the concentration at 11 p.m. was usually elevated above the normal range for that time of day. The patients with frequent episodes of hypertension showed the greatest elevation of the 11 p.m. concentration. Episodes of hypotension occurred in four patients, but were not associated with evidence of adrenal cortical exhaustion.

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