Myasthenia gravis and lymphoma. A clinical and immunological association

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Abstract
Myasthenia gravis and lymphoma rarely coexist, but the occurrence of myasthenia shortly after treatment of a patient with poorly differentiated nodular lymphoma suggested that an immunological disorder may have contributed to development of both diseases; fundamental defects in this association may be impaired immunological surveillance and impaired regulation of immune responses to autoantigens. The finding of T[thymus-derived]-cell immunodeficiency, including profound T cell lymphopenia, impaired delayed hypersensitivity responses and failure of a thymus-dependent antibody response to Salmonella adelaide flagellin, is consistent with this hypothesis.

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