Enantioselective Hydrolysis of 2, 2-Disubstituted Oxiranes Mediated by Microsomal Epoxide Hydrolase
- 1 November 1995
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 25 (21) , 3293-3306
- https://doi.org/10.1080/00397919508013848
Abstract
2-Aryl-2-methyloxiranes are enantioselectively hydrolyzed with microsomal epoxide hydrolase from pig liver to provide 1, 2-diols containing a tertiary benzylic alcohol stereogenic centre upto 34% enantio-meric purities.Keywords
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