Differences in effects of cigar and cigarette smoking on free fatty acid mobilization and catecholamine excretion

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Abstract
A study was made of the comparative effect of cigar and cigarette smoking on the mobilization of free fatty acids (FFA) and the excretion of catechol-amines. There was a greater increase in FFA concentration in the serum with cigarette than with cigar smoking. Inhaling during smoking caused a greater FFA response than not inhaling, with both cigars and cigarettes. With tobacco containing glucose randomly labeled with radioactive carbon (C14), there was a greater absorption of C14 with cigarette smoking. Urinary catecholamine excretion increased during smoking, significantly more with cigarettes than with cigars. The differences observed with the 2 forms of smoking probably result from the tendency to inhale with cigarette and not with cigar smoking and from the effect of this on nicotine absorption.