STIMULATION OF MACROPHAGE DNA-SYNTHESIS IN CULTURE BY DIFFERENT TYPES OF ACUTE NON IMMUNOLOGICAL INFLAMMATORY EXUDATES

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  • 1 January 1977
    • journal article
    • research article
    • Vol. 27  (1) , 19-22
Abstract
Acute non immunological inflammatory pleural exudates provoked by 4 different irritants and collected 4 h later, were capable of stimulating DNA synthesis in rat peritoneal macrophages in culture. A mitogenic factor, inflammatory mitogenic factor for macrophages [IMF (M)], could be responsible for this phenomenon. There may be a correlation between the protein concentration of the exudates and its mitogenic activity.

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