Immunosuppressive Treatment of Proliferative Glomerulonephritis

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Abstract
Glomerulonephritis of acute onset, most often post-streptococcal in etiology, tends to be a self-limited disease from which complete recovery is the rule. Nephritis of insidious onset, subacute or chronic in its course, for the most part has an uncertain prognosis except in the cases in which renal biopsy shows minimal or no glomerular changes. In the latter, often encountered in children, a favorable outcome can generally be anticipated regardless of therapy.In patients whose renal biopsy reveals membranous or proliferative changes, or both, the uncertainty of outcome has led to the experimental use of various modes of treatment. As long . . .