Comparison of the Proteolytic Specificities of Bovine and Porcine Pepsin A.

Abstract
Bovine pepsin A [EC 3.4.23.1] inactivates pancreatic RNase through a limited proteolysis the same way as does porcine pepsin A. The specific activity is lower and more dependent on the ionic strength. The proteolytic specificity of bovine pepsin A was investigated with B-chain of oxidized porcine insulin as the substrate. The specificity resembles qualitatively that of porcine pepsin but with quantitative differences.