Genome-Wide Transcriptional Profiles Are Consistent with Functional Specialization of the Extraocular Muscle Layers
- 1 September 2004
- journal article
- Published by Association for Research in Vision and Ophthalmology (ARVO) in Investigative Opthalmology & Visual Science
- Vol. 45 (9) , 3055-3066
- https://doi.org/10.1167/iovs.03-1385
Abstract
Purpose. Compartmentalization of the extraocular muscles into well-defined orbital and global layers is highly conserved. Recently, the active pulley hypothesis correlated the anatomic properties of orbital–global muscle layers with layer-specific division of labor. Microarray technology was used to identify muscle-layer–specific transcriptional profiles and, thereby, extend understanding of the structure-function characteristics of extraocular muscle layers.Keywords
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