Electrophoretic karyotypes in medically important Candida species.

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Abstract
Chromosomal DNAs from medically important Candida species were separated by pulse-field gel electrophoresis (PFGE). The banding patterns of 2 to 6 strains from individual species were examined for comparison. Variations occurred in the number of bands and their positions in the gel, not only among strains of different species but also among strains from the same species. However, some degrees of species-specific banding patterns were recognized. In C. krusei and C. guilliermondii, each banding pattern was similar to that of its relevant teleomorph. The phenomenon of colony-morphology switching occurred in most of those Candida species and, in some cases, the number of chromosomal bands varied in relation to the phenomenon.