Effects of Primary Allogeneic Tooth Transplants on Rejection of Skin Allografts in Rabbits

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Abstract
Investigation was made to evaluate the capacity of soft and hard dental tissues to stimulate an immune response demonstrable by the accelerated skin graft rejection response. Rabbit teeth and tooth fractions were transplanted to genetically dissimilar recipient rabbits and 3 weeks later recipients received skin grafts from respective dental tissue donors. Skin graft rejection response indicated that hard tooth material as well as pulp and perlodontal membrane induced tissue sensitivity as demonstrated by accelerated rejection of skin allografts taken from dental tissue donors. Additional consideration was given to site of transplantation of dental tissues.

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