Abstract
The finding that high doses (160 mg ) of Zn lowered high-density lipoprotein-cholesterol prompted the study of the effect of low-dose Zn supplementation on lipoprotein values in sedentary and endurance-trained men. Endurance-trained (21) and sedentary (23) men received either placebo or 50 mg of ZnSO4 daily for 8 wk. Despite the fact that plasma Zn increased 15%, fasting plasma high-density-lipoprotein cholesterol, total cholesterol, low-density-lipoprotein cholesterol and triglyceride levels did not change in response to Zn ingestion. Low-dose Zn supplementation does not affect lipid or lipoprotein values in either endurance-trained or sedentary men [This study was significant for coronary artery disease.].