Evidence for the Co‐Expression of Oxytocin and Vasopressin Messenger Ribonucleic Acids in Magnocellular Neurosecretory Cells: Simultaneous Demonstration of Two Neurohypophysin Messenger Ribonucleic Acids by Hybridization Histochemistry
- 1 June 1990
- journal article
- research article
- Published by Wiley in Journal of Neuroendocrinology
- Vol. 2 (3) , 257-259
- https://doi.org/10.1111/j.1365-2826.1990.tb00401.x
Abstract
A novel enzyme-labelled oligonucleotide probe specific for oxytocin messenger ribonucleic acid (mRNA) and a radiolabelled oligonucleotide probe specific for vasopressin mRNA were used together to visualize both oxytocin and vasopressin mRNA''s in hypothalamus sections from salt loaded (2% saline) rats. The results demonstrates that the majority of magnocellular neurons contain only oxytocin or vasopressin mRNA, however a small number of neurons, 1% to 2%, contained both oxytocin and vasopressin transcripts.Keywords
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