N,N′-dibenzoylcystine as an efficient chiral auxiliary for asymmetric reduction of ketones with lithium borohydride
- 1 January 1984
- journal article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 7,p. 413-414
- https://doi.org/10.1039/c39840000413
Abstract
Aromatic and α,β-unsaturated ketones were reduced enantioselectively with lithium borohydride in the presence of N,N′-dibenzoylaystine and t-butyl alcohol to afford optically active secondary alcohols with high enantiomeric excesses (76–90%e.e.).Keywords
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