Selective Ablation of Porcine and Rabbit Liver Tissue Using Radiofrequency: Preclinical Study

1 October 1999

journal article
research article
Published by S. Karger AG in European Surgical Research

Vol. 31 (5) , 371-379
https://doi.org/10.1159/000008715

Abstract

Temperature changes and their distribution induced by 13.56-MHz radiofrequency (RF) heating of agar phantom and porcine and rabbit liver were investigated. It was possible to produce selective local heating of approximately 50°C in the RF field of 2 × 2 × 2 cm³ of the pig or rabbit liver. Coagulation necrosis after heating became pronounced and the margin between the coagulated lesion and normal tissue became clearer with time. Within 1 week after RF heating at 50°C for 20 min, the coagulated area was replaced selectively and totally by necrotic tissue.

Keywords

This publication has 2 references indexed in Scilit:

Radiofrequency Ablation of Porcine Liver In Vivo
Annals of Surgery, 1998
Tumor eradication by radiofrequency therapy. Responses in 21 patients
JAMA, 1976