Imidazo[4,5-f]quinolines. 4. Synthesis and anthelmintic activity of a series of imidazo[4,5-f]quinolin-9-ols

Abstract
A series of 2-arylimidazo[4,5-f]quinolin-9-ols was prepared by a multistep procedure from various 5-aminobenzimidazoles. These compounds possess a significant degree of anthelmintic activity against the mouse tapeworm Hymenolepis nana. The most active compound is the 2-(2-furyl) analogue. Additional anthelmintic testing is reported for this compound.