Pseudoephedrine Dangers

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Abstract
To the Editor.— Pseudoephedrine is an over-the-counter amphetamine commonly used as a decongestant. Pseudoephedrine is a mixed-acting sympathomimetic amine, causing both the release of neurotransmitters from adrenergic nerve endings and the direct stimulation of adrenergic receptors. While overdoses of other amphetamines can produce a life-threatening adrenergic crisis comprising hypertension, tachycardia, hyperthermia, agitation, and convulsions, serious overdoses with pseudoephedrine alone are rare.1-3 We report the case of a child who suffered a generalized seizure after ingesting pseudoephedrine tablets, a finding not previously reported after isolated pseudoephedrine ingestions.

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