Radioresistance of Cells Responsible for Delayed Hypersensitivity Reactions in the Mouse
Open Access
- 1 August 1975
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 115 (2) , 606-608
- https://doi.org/10.4049/jimmunol.115.2.606
Abstract
Summary: The cells responsible for delayed hypersensitivity reactivity in the mouse act in a radioresistant fashion only if such irradiated cells are injected directly into the site of antigen challenge. Intravenous transfer of irradiated, primed spleen cells does not achieve a transfer of sensitivity to show delayed type hypersensitivity reactions. Transfer of sensitivity by the intravenous route can be effected by injection of non-irradiated spleen cells from primed mice.Keywords
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