ERYTHROCYTE METABOLISM. THE METABOLIC BEHAVIOR OF THE CHOLESTEROL OF HUMAN ERYTHROCYTES 1

Publisher Website
Google Scholar
Abstract
In 2 human subjects, in whose body water an elevated concn. of D was maintained by the admn. of D2O, the rise in concn. of D in the cholesterol of the erythrocytes was similar to its rise in the cholesterol of the plasma. This finding and the demonstration of a relatively insignificant degree of synthesis of cholesterol by human erythro-cytes in vitro favor the conclusion that the cholesterol of human erythrocytes is in dynamic exchange with the cholesterol of the plasma. The possible relevance of the metabolic lability of the cholesterol of erythrocytes to the problem of the ageing process in the human erythrocyte is indicated.