Metabolism of tetraorganolead compounds by rat-liver microsomal mono-oxygenase: I. Analytical methods for quantitative determination of dealkylation products
- 1 January 1983
- journal article
- research article
- Published by Taylor & Francis in Xenobiotica
- Vol. 13 (10) , 577-581
- https://doi.org/10.3109/00498258309052216
Abstract
1. Different methods have been examined for the separation and determination of the triethyl lead ion in the presence of tetraethyl lead in biological material. 2. Quantitative recovery of triethyl lead, and a limit of detection of 8M, were obtained with selective chromatography on kieselguhr (Extrelut®) in combination with atomic absorption spectrometry.Keywords
This publication has 13 references indexed in Scilit:
- Metabolism of tetraorganolead compounds by rat-liver microsomal mono-oxygenase: II. Enzymic dealkylation of tetraethyl leadXenobiotica, 1983
- A simplification of the protein assay method of Lowry et al. which is more generally applicableAnalytical Biochemistry, 1977
- Bioorganotin chemistry. Metabolism of organotin compounds in microsomal monooxygenase systems and in mammalsJournal of Agricultural and Food Chemistry, 1977
- Bioorganotin chemistry: Reactions of tributyltin derivatives with a cytochrome P-450 dependent monooxygenase enzyme systemJournal of Organometallic Chemistry, 1976
- Bioorganotin chemistry: biological oxidation of tributyltin derivativesJournal of Organometallic Chemistry, 1975
- Oxidative Dealkylation of Tetra-, Tri-, and Dialkyltins and Tetra- and Trialkylleads by Liver Microsomes.Acta Chemica Scandinavica, 1971
- Polarographic Determination of Hexaethyldilead in TetraethylleadAnalytical Chemistry, 1959
- Organische, mit Wasser nicht mischbare Lösungsmittel in der FlammenphotometrieAnalytical and Bioanalytical Chemistry, 1958
- Über die Verwendung von substituierten Dithiocarbamaten in der Mikroanalyse. IIIMicrochimica Acta, 1955
- Tetra-Ethyl Lead PoisoningBMJ, 1946