No difference in N-terminal pro-brain natriuretic peptide (NT-proBNP) concentrations between endurance athletes with athlete's heart and healthy untrained controls
Open Access
- 1 September 2004
- Vol. 90 (9) , 1055-1056
- https://doi.org/10.1136/hrt.2003.020420
Abstract
In contrast to atrial natriuretic peptide, which refers to atrial stretch, BNP refers to ventricular strain. Synthesised by cardiomyocytes in response to ventricular overload and elevated myocardial wall stress,2 resting concentrations of BNP and its cleaved precursor peptide N-terminal pro-BNP (NT-proBNP) have become useful markers to assess cardiac dysfunction, chronic heart failure, and left ventricular (LV) hypertrophy caused by hypertension or cardiomyopathy. In British Army recruits an association between the increase in LV mass and elevated resting BNP concentrations after a 10 week training period was demonstrated by Montgomery and colleagues3 However, in another study, BNP concentrations did not correlate with echocardiographically determined LV mass in a small group of eight cyclists with athlete’s heart.4Keywords
This publication has 5 references indexed in Scilit:
- Athlete’s heartJournal of the American College of Cardiology, 2002
- B-Type Natriuretic Peptide Is Related to Left Ventricular Mass in Hypertensive Patients but Not in AthletesCardiology, 2002
- B-type natriuretic peptide levels: A potential novel “white count” for congestive heart failureJournal of Cardiac Failure, 2001
- Sports-Specific Adaptations and Differentiation of the Athlete??s HeartSports Medicine, 1999
- Association of Angiotensin-Converting Enzyme Gene I/D Polymorphism With Change in Left Ventricular Mass in Response to Physical TrainingCirculation, 1997