Progesterone Retards Postpartum Involution of the Rabbit Myometrium
- 15 April 1966
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 152 (3720) , 356-358
- https://doi.org/10.1126/science.152.3720.356
Abstract
Postpartum involution of the uterus was significantly reduced in rabbits by immediate and repeated injections of progesterone. Progesterone had no effect if the injections commenced 24 hours after delivery. The decrease in concentration of progesterone that accompanies birth results in release of proteolytic and other degradative enzymes from subcellular particles; these enzymes cause the involution, and, once the enzymes are released into the cellular milieu, progesterone has no effect.This publication has 9 references indexed in Scilit:
- Degradative enzymes in the uterine myometrium of rabbits under different hormonal conditionsArchives of Biochemistry and Biophysics, 1965
- Stretch-Induced Uterine Growth, Protein Synthesis and FunctionNature, 1965
- FORMATION AND BREAKDOWN OF COLLAGEN AND ELASTIN IN THE HUMAN UTERUS DURING PREGNANCY AND POST-PARTUM INVOLUTIONBiochemical Journal, 1963
- Catabolism of collagen and non-collagen protein in the rat uterus during post-partum involutionBiochemical Journal, 1962
- Connective tissue changes in postpartum uterine involution in the albino ratThe Anatomical Record, 1960
- CONCENTRATION OF PROGESTIN IN THE SERUM OF THE RABBIT DURING PREGNANCY, THE PUERPERIUM AND FOLLOWING CASTRATION12Endocrinology, 1955
- The effects of lactation on the postpartum involution of the uterus of the catJournal of Anatomy, 1946
- HORMONIC AND PHYSICAL FACTORS IN UTERINE GROWTHCold Spring Harbor Symposia on Quantitative Biology, 1937
- THE INVOLUTION OF THE UTERUS FOLLOWING LABOR AND THE INFLUENCE OF CASTRATION AND SUCKLING ON THE PROCESS OF INVOLUTIONAmerican Journal of Physiology-Legacy Content, 1921