Role of microorganisms in dandruff

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Abstract
The role of microorganisms in dandruff was studied by suppressing individually and then collectively the 3 major components of the scalp microflora [Pityrosporum, aerobic coagulase-negative cocci, Propionibacterium acnes]. The effect on dandruff was assessed subjectively by clinical grading and objectively by the corneocyte count. No effect on dandruff was demonstrated when scalp organisms were suppressed. Dandruff was suppressed by SeS2 shampooing, and the effect of continued suppression of Pityrosporum with topically applied amphotericin was measured. Dandruff returned to pretreatment levels despite continued suppression of Pityrosporum. The increased number of scalp microorganisms found in dandruff occurs secondarily to increased nutrients and plays no primary role on the pathogenesis of dandruff.

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