Temperature-sensitive Mutants of the Streptomyces Plasmid pIJ702

Abstract
DNA from the Streptomyces plasmid pIJ702 was mutagenized in vitro using hydroxylamine and transformed into S. lividans. One plasmid with temperature-sensitive replication (pMT660) and 1 plasmid with a temperature-sensitive tyrosinase (pMT661) were isolated. Plasmid pMT661 contains a novel PstI restriction endonuclease site within the tyrosinase gene.

This publication has 1 reference indexed in Scilit: