The anti-chlamydial effect of experimental Mycoplasma pulmonis infection in the murine genital tract

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Abstract
Experimental Chlamydia trachomatis infection of the genital tract of female CBA and TO mice was greatly curtailed by a concurrent genital infection with Mycoplasma pulmonis. TO mice in which chlamydial infection had been suppressed by the mycoplasma infection were treated with the anti-mycoplasma agent, gentamicin. This did not cause a reappearance of the chlamydiae, suggesting that these organisms had been eliminated completely. The M. pulmonis infection stimulated a striking and persistent polymorphonuclear leukocyte response, which may have been the cause of the curtailment of the chlamydial infection.

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